CellzDirect is building a preeminent cell-based bioscience company that provides innovative ADME products and services to expedite the development of safe, effective drugs.

Our Company

Now part of the Invitrogen family, CellzDirect provides high-quality in vitro ADME cell products and contract laboratory and consulting services focused primarily on drug metabolism and transport. Our clients include leaders in the pharmaceutical, biotech, academic, chemical and consumer products fields as well as government agencies.  With CellzDirect’s support, scientists conduct research that accelerates the discovery of safe and effective drugs.

CellzDirect offers a complete line of fresh and cryopreserved hepatocytes and liver subcellular fractions, and transporters derived from a variety of species, including human, non-human primate, dog, rat and mouse.  Members of our scientific staff have dedicated up to 20 years on research to optimize the isolation conditions and culture techniques by species.

Our service offerings include drug-drug interaction studies, drug metabolism studies and hepatotoxicity studies, such as enzyme induction and inhibition, reaction phenotyping, metabolite stability and profiling, and P-gp assays. These studies can be conducted in GLP (Good Laboratory Practices) or non-GLP formats, and study data can be presented for FDA submissions.